Research Article

Angiogenic and Vasculogenic Factors in the Vitreous from Patients with Proliferative Diabetic Retinopathy

Table 1

Clinical characteristics and levels of angiogenic and vasculogenic factors in 15 control patients.

Age (yr)/sexDuration of symptoms (days)Status of lensExtent of detachment (quadrants)VEGF (pg/mL)
(detection limit: 9.0 pg/mL)
sVEGFR-2 (pg·mL) (detection limit: 4.6 pg/mL)SCF (pg/mL) (detection limit: 9.0 pg/mL)s-Kit (pg/mL) (detection limit: 65 pg/mL)PGE2 (pg/mL) (detection limit: 25 pg/mL)eNOS (pg/mL) (detection limit: 15 pg/mL)

78/M4Pseudophakic219.3837.4ND8768.2ND
60/F3Pseudophakic238.8161.2NDND78.8ND
47/M6Pseudophakic4ND1126.6128.424738ND
48/F5Phakic2ND1730.7NDND42.8ND
59/M3Phakic2ND1016.222.216380.2ND
38/F14Phakic233.193NDND28.1ND
40/M5Phakic3ND915.359.113520.7ND
27/F7Phakic2ND656.2ND224.970.8ND
65/F10Pseudophakic427.7783ND17363.9ND
55/M2Phakic226.4304.4NDND45ND
40/F4Aphakic2ND912.5NDND61.3ND
70/M2Pseudophakic216.5934.437.65867.3ND
74/M3Pseudophakic121664.4ND13763.2ND
63/M2Pseudophakic230.8140.7NDND80.3ND
50/M5Pseudophakic3ND731.276.7ND61.7ND

VEGF: vascular endothelial growth factor; sVEGFR-2: soluble vascular endothelial growth factor receptor-2; SCF: stem cell factor; s-kit: soluble c-kit; PGE2: prostaglandin E2; eNOS: endothelial nitric oxide synthase; ND: not detected.