Journal of Diabetes Research / 2013 / Article / Tab 1

Research Article

Adipocytokine Associations with Insulin Resistance in British South Asians

Table 1

Biomedical characteristics of the study population defined by normal glucose tolerance (NGT), impaired glucose tolerance (IGT), and newly diagnosed type 2 Diabetes (T2DM).

NGTIGTT2DMP   
NGT versus T2DM
P   
IGT versus T2DM

n 794039
Age (years)52.1 ± 9.8 55.1 ± 11.7 52.7 ± 9.2 0.08 0.18
Male sex40 (50)22 (54)17 (44) 0.37 0.96
Active Smoking 8 (10) 6 (15)6 (15) 0.71 0.85
BMI (kgm−2) 26.6 ± 4.229.1 ± 4.930.1 ± 5.8 0.01 0.26
Waist circumference (cm)92.7 ± 10.696.9 ± 10.1100.8 ± 10.1 <0.01 0.04
WHR 0.88 ± 0.080.91 ± 0.080.95 ± 0.08 <0.01<0.01
SBP (mmHg) 135.3 ± 19.3139.5 ± 20.6144.3 ± 18.5 0.11 0.18
DBP (mmHg) 85.4 ± 10.7 86.3 ± 8.2 89.7 ± 9.1 0.52 0.07
Total cholesterol (mmoll−1)5.3 ± 1.05.2 ± 1.15.3 ± 1.1 0.63 0.58
HDL-C (mmoll−1) 1.3 ± 0.31.2 ± 0.31.1 ± 0.2 0.12 0.01
Triglycerides (mmoll−1)*1.4 (0.8) 1.7 (1.2) 2.6 (2.1) 0.03 0.04
FPG (mmoll−1) 5.0 ± 0.55.4 ± 0.68.1 ± 2.1 0.02<0.01
2 h PLG (mmoll−1)5.4 ± 1.28.9 ± 1.514.9 ± 3.9 <0.01<0.01
HOMA-IR (arb.)*1.6 (1.2) 2.5 (1.8)6.0 (4.9) <0.01<0.01
CVD medication
Antihypertensive14 (18)15 (34)14 (36) 0.01 0.33
Lipid lowering16 (21)12 (29)11 (28) 0.03 0.89

Data are means ± standard deviation (SD) or median with inter quartile range (IQR)* and n (%). WC: waist circumference, WHR: waist Hip Ratio, SBP: systolic blood pressure, DBP: diastolic blood pressure, HDL-C: high-density lipoprotein cholesterol subfraction, FPG: fasting plasma glucose, 2-h PLG: 2 hour post-load (75g-oral glucose tolerance test) glucose. HOMA-IR: homeostasis model insulin resistance.

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