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Journal of Diabetes Research
Volume 2013, Article ID 591574, 6 pages
Clinical Study

Exploring the Variability in Acute Glycemic Responses to Exercise in Type 2 Diabetes

1Faculty of Physical Education & Recreation, University of AB, 1-059 Li Ka Shing Center, Edmonton, AB, Canada T6G 2H9
2Department of Agricultural, Food and Nutritional Science, University of AB, 2-012D Li Ka Shing Center, Health Research Innovation, Edmonton, AB, Canada T6G 2H9

Received 2 March 2013; Revised 30 May 2013; Accepted 10 June 2013

Academic Editor: Francesco Chiarelli

Copyright © 2013 Tasuku Terada et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Aim. To explore the factors associated with exercise-induced acute capillary glucose (CapBG) changes in individuals with type 2 diabetes (T2D). Methods. Fifteen individuals with T2D were randomly assigned to energy-matched high intensity interval exercise (HI-IE) and moderate intensity continuous exercise (MI-CE) interventions and performed a designated exercise protocol 5 days per week for 12 weeks. The duration of exercise progressed from 30 to 60 minutes. CapBG was measured immediately before and after each exercise session. Timing of food and antihyperglycemic medication intake prior to exercise was recorded. Results. Overall, the mean CapBG was lowered by 1.9 mmol/L ( ) with the change ranging from −8.9 to +2.7 mmol/L. Preexercise CapBG (44%; ), medication (5%; ), food intake (4%; ), exercise duration (5%; ), and exercise intensity (1%; ) were all associated with CapBG changes, explaining 59% of the variability. Conclusion. The greater reduction in CapBG seen in individuals with higher preexercise CapBG may suggest the importance of exercise in the population with elevated glycemia. Lower blood glucose can be achieved with moderate intensity exercise, but prolonging exercise duration and/or including brief bouts of intense exercise accentuate the reduction, which can further be magnified by performing exercise after meals and antihyperglycemic medication. This trial is registered with NCT01144078.