Dose Effect and Mode of Inheritance of Diabetogenic Gene on Mouse Chromosome 11

Figure 1

Intraperitoneal glucose tolerance test at 48 weeks of age in heterozygous C3H-11^NSY (𝑛=8, white triangles), C3H mice (𝑛=8; white circles), and homozygous C3H-11^NSY (𝑛=28, black circles, [6]). Values are mean ± SEM. *𝑃<0.05 compared with C3H mice (Mann-Whitney 𝑈 test). ^††𝑃<0.01 and ^†††𝑃<0.001 compared with heterozygous C3H-11^NSY (Mann-Whitney 𝑈 test).