608923.fig.002a
(a)
608923.fig.002b
(b)
Figure 2: Streptozotocin sensitivity at 12 weeks of age in heterozygous C3H-11NSY ( , white triangles), C3H mice ( ; white circles), and homozygous C3H-11NSY ( , black circles, [7]). The glucose concentration was determined 0, 1, 2, 4, 5, 7, and 8 days after a single intraperitoneal injection of streptozotocin at 175 mg/kg body weight. Blood glucose concentrations are presented as mean ± SEM (a). The percentage of animals free of hyperglycemia (blood glucose level >11.1 mmol/L) is shown (b). * , ** , and *** compared with C3H and , †† , and ††† compared with heterozygous C3H-11NSY (Mann-Whitney test for (a), log-rank test for (b)).