Nearby Construction Impedes the Progression to Overt Autoimmune Diabetes in NOD Mice

Figure 2

The lower incidence of diabetes is not due to a genetic drift in our colony. The onset of diabetes was monitored in six female NOD mice from the NOD/LtJ-HMR mouse colony born more than two months after the construction had been completed (open circles) as well as from twenty female NOD/ShiLtJ mice bought from Jackson Labs and maintained at the HMR facility (closed triangles). The cumulative diabetes incidence shows no difference between these two colonies. Log-rank test, 𝑃 value = 0.4142.