The Inhibitor U0126 Attenuates Diabetes-Induced Upregulation of MMP-9 and Biomarkers of Inflammation in the Retina
Figure 3
Effect of inhibitor (U0126) on diabetes induced iNOS, IL-6, and TNF-α upregulation in diabetic retina. (a) Protein expression of iNOS, (b) IL-6, and (c) TNF-α was measured by western blot and β-actin was used as housekeeping control. Each measurement was performed at least three times. Results are expressed as mean ± s.d. of at least six rats in each group. compared with normal rats and compared to diabetic rats. N, D, and D + U0126 = normal, 1 week diabetic and U0126 pretreated diabetic rat.
