The Effect of Dantonic Pill on β-Catenin Expression in a Rat Model of Streptozotocin-Induced Early Stage of Diabetic Nephropathy
Figure 2
Effect of DP and irbesartan treatments on the renal expressions of -catenin in the rats. (a) Effect of DP and irbesartan treatments on the renal mRNA and protein expressions of -catenin as described in the materials and methods section. (A) The relative levels of the -catenin mRNA were assessed by real-time PCR, and the results were normalized to -actin. (B) The expression of the -catenin protein expressed as a quantitative estimate score. (b) The protein expression specific to -catenin ((A)–(D)) detected by immunohistochemistry (400x magnification): (A) normal glomerulus in the control; (B) STZ + vehicle group; (C) STZ + irbesartan (50 mg/(kg·day)) group; and (D) STZ + DP (500 mg/(kg·day)) group. All values are the means ± SD (). *, compared with the STZ + vehicle group.
