Clinical Study
Retinal Layers Changes in Human Preclinical and Early Clinical Diabetic Retinopathy Support Early Retinal Neuronal and Müller Cells Alterations
Figure 3
Graphs showing specific retinal layer thickness in normal subjects (control), diabetics without retinopathy (no DR), and diabetics with nonproliferative diabetic retinopathy (NPDR) determined automatically by spectral domain OCT in 4 peripapillary areas (temporal, superior, nasal, and inferior). (a) Inner limiting membrane + nerve fibre layer (ILM + RNFL); (b) ganglion cell layer + inner plexiform layer (GCL + IPL); (c) inner nuclear layer + outer plexiform layer (INL + OPL); (d) outer nuclear layer + external limiting membrane (ONL + ELM); and (e) inner segment/outer segment photoreceptor layer + retinal pigment epithelium (IS/OS + RPE). There is no significant difference in the retinal layer thickness among the controls, no DR, and NPDR groups.
