Effects of Acute Exercise and Chronic Exercise on the Liver Leptin-AMPK-ACC Signaling Pathway in Rats with Type 2 Diabetes

Figure 1

Histograph showing the effects of exercise on the leptin-AMPK-ACC pathway in type 2 diabetes rats. The relative levels of protein phosphorylation and protein expression related to the leptin-AMPK-ACC signaling pathway on different groups were shown. (a) Leptin and its receptor. (b) AMPK1/2 and p-AMPK1/2 (Thr¹⁷²). (c) AMPKα1 and p-AMPKα1 (Thr¹⁷²). (d) AMPKα2 and p-AMPKα2 (Thr¹⁷²). (e) ACC and p-ACC (Ser⁷⁹). Note: in comparison with the control group: **𝑃<0.01, *𝑃<0.05; in comparison with the diabetes group: ^##𝑃<0.01, ^#𝑃<0.05 (𝑛=8).

(a)

(b)

(c)

(d)

(e)