Effects of Acute Exercise and Chronic Exercise on the Liver Leptin-AMPK-ACC Signaling Pathway in Rats with Type 2 Diabetes

Table 1

Body weight and biochemical parameters of different groups.

	CON	DC	DCE	DAE
Weight (g)	520.7±12.00	502.8±10.51	527.3±10.77	507.3±13.16
Epididymal fat (g)	8.83±0.43	7.86±0.34	8.61±0.44	8.12±0.45
Insulin (pmol/L)	66.14±2.80	76.29±4.17	70.86±3.61	68.70±3.34
FBG (mmol/L)	5.35±0.23	13.18±0.52^∗∗	11.57±0.42^#	11.51±0.41^#
Kitt (%/min)	3.19±0.19	1.95±0.30^∗∗	2.87±0.22^#	2.61±0.15^#
TG (mmol/L)	1.68±0.09	2.06±0.11^∗∗	1.79±0.10^#	2.12±0.07^$
TC (mmol/L)	4.15±0.26	5.78±0.39^∗∗	4.69±0.21^#	5.67±0.35^$
FFA (mmol/L)	0.39±0.01	0.63±0.05^∗∗	0.49±0.04^#	0.60±0.04
HDL-C (mmol/L)	1.730±0.33	1.029±0.10^∗∗	1.358±0.16^#	0.94±0.29
LDL-C (mmol/L)	0.27±0.12	1.21±0.24^∗∗	0.51±0.19^##	1.25±0.35^$$
Leptin (ng/mL)	3.25±0.38	5.39±0.64^∗∗	4.41±0.61^#	5.28±0.49

Results were expressed as mean ± standard error (𝑛=7-8). Differences between groups were compared by one-way analysis of variance (ANOVA).
Note: in comparison with the control group: ^∗∗𝑃<0.01, ^∗𝑃<0.05; in comparison with the diabetes group: ^##𝑃<0.01, ^#𝑃<0.05; in comparison with the chronic exercise group: ^$$𝑃<0.01, ^$𝑃<0.05.