Variations in Rodent Models of Type 1 Diabetes: Islet Morphology
Figure 10
Human islet morphology and infiltration. (a) An islet from nondiabetic human donor was large with a normal cellular morphology. Scale bar = 100 μm for both images. (b) An example of an islet from a donor with controlled diabetes showed a lack of β-cells. (c) Glucagon staining illustrates the lack of infiltration in the healthy donor. (d) The donor with long-standing diabetes also had no signs of infiltration.