The Impact of Hyperglycemic Emergencies on the Kidney and Liver

Table 4

Clinical and biochemical characteristics of the mild/moderate and severe DKA patients at admission.

Variables	Mild/moderate DKA; (𝑛=25)	Severe DKA; (𝑛=15)	𝑃 value
Female/male (𝑛/𝑛)	15/10	7/8	0.517
Age (years)	48±22	41±14	0.198
Duration of diabetes (years)	8.00 (0.00–26.00)	5.00 (0.00–15.00)	0.134
Plasma glucose (mmol/L)	29.22±9.24	28.94±7.32	0.914
HbA1c (%)	12.35±2.72	12.54±1.72	0.837
Arterial pH	6.93±0.10	7.18±0.05	<0.001
HCO3 (mmol/L)	8.35±3.17	3.27±1.80	<0.001
Alanine aminotransferase (U/L)	14.37±5.58	16.32±6.06	0.445
Aspartate aminotransferase (U/L)	19.88±7.47	18.16±11.51	0.702
𝛾-glutamyl transpeptidase (U/L)	15.50±3.96	19.06±7.83	0.239
Total bilirubin (μmol/L)	11.39±3.39	11.19±4.89	0.926
Direct bilirubin (μmol/L)	4.34±0.98	4.69±1.82	0.641
Total protein (g/L)	58.81±8.26	59.66±10.18	0.838
Albumin (g/L)	37.07±4.48	35.32±5.54	0.309
Globulin (g/L)	23.39±6.07	24.51±6.60	0.686
Prealbumin (mg/dL)	171.94±52.78	119.66±35.44	0.010
Serum creatinine (μmol/L)	117.44±97.55	105.04±58.94	0.618
eGFR (mL/min per 1.73 m^2)	59.27±25.91	60.28±26.08	0.906
Uric acid (μmol/L)	412.09±168.84	490.44±124.85	0.192

All values in the table are given as the mean ± standard deviation, except for the duration of diabetes, which is given as the median and range (min–max).