Figure 2: Pedigree maps and general profiles of SDT rats. Pedigree maps of nucleus line (a) and basic profiles of SDT rats. The cumulative incidence of DM was 100% at 40 weeks in male SDT rats (b) and the survival rates at 65 weeks was over 90% (c). The plasma glucose levels in male SDT rats reached 700 mg/dL by 25 weeks (d) and a decrease in body weight was observed from 20 weeks (e). Green square: male SDT rats, pink circle: female SDT rats. Open symbols represent male or female SD rats. Data represent means ± SD ( –8). , (versus age-matched SD rats, unpaired t-test). Figures are modified from [4, 6].