Mediation Role of C-Reactive Protein on the Association between Smoking Quantity and Type 2 Diabetes in Current Chinese Smokers

Table 4

The association between number of cigarettes smoked per day and type 2 diabetes and the mediation by CRP in 984 Chinese current smokers (OR; 95% CI)^#.

Model	Adjustments	Number of cigarettes smoked per day			Inflammatory markers				Nagelkerke 𝑅^2 (%)
		≤10	11~20	>20	Quartile 1	Quartile 2	Quartile 3	Quartile 4
1	Smoking	1	0.84; (0.54–1.31)	1.91*; (1.03–3.57)	—	—	—	—	1.10
2	Model 1; + confounders of age, and so forth	1	0.94; (0.60–1.49)	2.12*; (1.10–4.14)	—	—	—	—	2.90
2a	Model 2; + CRP	1	0.84; (0.52–1.34)	1.60; (0.81–3.17)	1	0.84; (0.41–1.73)	1.64; (0.87–3.06)	1.87*; (1.01–3.47)	4.70

#The adjusted OR was calculated by binary logistic regression models with adjustment for age, gender, occupation, education, family monthly income, family history of diabetes, alcohol consumption, and exercise.
^∗𝑃<0.05.