Table 1: Clinical characteristics of subjects.

VariableEntire sample Subjects without CANSubjects with CAN value*

Demographic information
20961705387
 Age (years) <0.001
 Gender male, (%)705 (33.7%)562 (32.96%)143 (36.95%)0.134
 BMI (kg/m2) <0.001
 WC (cm) <0.001
 SBP (mmHg) <0.001
 DBP (mmHg) 0.001
Medical history
 Smoking yes, (%)306 (14.63%)244 (14.31%)62 (16.02%)0.390
 MetS yes, (%)833 (39.82%)629 (36.89%)204 (52.71%)<0.001
 HT yes, (%)976 (46.65%)735 (43.11%)241 (62.27%)<0.001
 DM yes, (%)446 (21.33%)307 (18.02%)139 (35.92%)<0.001
Laboratory measurement
 FPG (mmol/L) <0.001
 PBG (mmol/L) <0.001
 HbAlc (%) <0.001
 FINS ( ml/L) <0.001
 IR (mmol/L) <0.001
 TC (mmol/L) 0.142
 TG (mmol/L) <0.001
 HDL (mmol/L) 0.203
 LDL (mmol/L) 0.229
 SCr ( mol/L) 0.561
 UA ( mol/L) 0.216
HRV indices
 HR (bpm) <0.001
 TP (ms2) <0.001
 LF (ms2) <0.001
 HF (ms2) <0.001
 LF/HF <0.001

Note: *presents the difference between subjects with and without cardiovascular autonomic neuropathy (CAN). BMI: body mass index; WC: waist circumference; SBP: systolic blood pressure; DBP: diastolic blood pressure; FPG: fasting plasma glucose; PBG: plasma blood glucose; FINS: fasting blood insulin; IR: insulin resistance; TC: serum total cholesterol; TG: triglyceride; UA: uric acid; HDL: high-density lipoprotein cholesterol; LDL: low density lipoprotein cholesterol; SCr: serum creatinine; HR: heart rate; TP: total power of variance; LF: low frequency; HF: high frequency; MetS: metabolic syndrome; DM: diabetes; HT: hypertension.