Effects of Simvastatin on Glucose Metabolism in Mouse MIN6 Cells

Figure 6

Effects of simvastatin on I _KATP and current density in MIN6 cells (^∗𝑃<0.05, ^∗∗𝑃=0.03, and ^∗∗∗𝑃<0.01). (a) KATP current of control group (𝑛=12), (b) KATP current with application of 2 μmol/L simvastatin (𝑛=12), (c) KATP current with application of 5 μmol/L simvastatin (𝑛=10), (d) KATP current with application of 10 μmol/L simvastatin (𝑛=8), (e) current density-voltage (J-V) curves of four groups, and (f) the current densities of cells with application of different concentrations of simvastatin at 80 mV voltage.

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