Effects of Simvastatin on Glucose Metabolism in Mouse MIN6 Cells

Table 2

Effects of simvastatin on insulin content, secretion in MIN6 cells, and total insulin at low glucose levels (mean ± SD, 𝑛=6, 𝜇IU/mg protein).

Group	Insulin secretion	Insulin content	Total amount of insulin
Group NC	62.12 ± 4.03	540.32 ± 56.75	602.43 ± 53.41
Group A	36.82 ± 9.20	357.17 ± 34.09	393.98 ± 34.33
Group B	10.00 ± 5.90	235.53 ± 68.70	245.53 ± 63.44
Group C	4.78 ± 2.05	231.02 ± 45.13	235.80 ± 46.36
𝐹 value	80.16	30.26	46.04
𝑃 value	<0.001	<0.001	<0.001