Effects of Simvastatin on Glucose Metabolism in Mouse MIN6 Cells

Table 3

Effects of simvastatin on insulin content, secretion in MIN6 cells, and total insulin at high glucose levels (mean ± SD, 𝑛=6, 𝜇IU/mg protein).

Groups	Insulin secretion	Insulin content	Total amount of insulin
Group NC	98.53 ± 6.69	720.17 ± 59.66	818.69 ± 58.78
Group A	102.63 ± 23.13	471.09 ± 103.48	573.72 ± 98.43
Group B	106.49 ± 5.91	378.40 ± 75.83	484.88 ± 79.05
Group C	69.24 ± 9.25	288.29 ± 122.58	357.53 ± 114.43
𝐹 value	6.58	15.81	18.67
𝑃 value	0.007	<0.001	<0.001