TNF-α and Microalbuminuria in Patients with Type 2 Diabetes Mellitus
Table 3
Demographic, anthropometric, and clinical characteristics, prescribed drugs, and laboratory findings in diabetic patients with normoalbuminuria and microalbuminuria.
Parameter
Normoalbuminuric
Microalbuminuric
()
()
Age (years)
64 (37–78)
70
Sex (male/female)
17/28 (37.8/62.2)
15/18 (45.5/54.5)
Duration of DM (years)
12 (1–38)
18
Body mass index (kg/m2)
27 ± 5.1
28.5 ± 4.5
Mean blood pressure (mmHg)
98.33 ± 8.6
101 ± 8.57
Systolic blood pressure (mmHg)
133.4 ± 13.1
137.9 ± 13.1
Diastolic blood pressure (mmHg)
80.8 ± 9.9
82.6 ± 9.2
Hypertension
23 (51.1)
29 (87.9)
Cardiovascular disease
13 (28.8)
19
Retinopathy
12 (30)
19
Diabetic neuropathy
19 (50)
17
Statins
32 (71.1)
28 (84.8)
Acetylosalicylic acid
12 (26.7)
9 (27.3)
Clopidogrel
9 (20)
14 (42.4)
ACEi/ARBs
18 (40)
27 (81.8)∧
Fibrinogen (g/L)
3.3 ± 0.45
3.26 ± 0.67
Glycosylated hemoglobin (%)
6.7 ± 0.7
7.06 ± 0.5∧
Total cholesterol (mg/dl)
177.2 ± 38.1
171.7 ± 33.4
LDL cholesterol (mg/dl)
108.5 ± 26.6
104.5 ± 25.9
HDL cholesterol (mg/dl)
46.96 ± 9.1
43.18 ± 9.28
Triglycerides (mg/dl)
125.8 ± 56.9
129.9 ± 46.5
C-reactive protein (mg/dl)
0.53 (0.22–1.9)
0.53 (0.13–0.79)
Serum TNF- (pg/ml)
3.79 ± 5.1
4.99 ± 5.06
Urinary TNF- (pg/mg creatinine)
3.8 ± 3.3
11.4 ± 10.3∧
eGFR (ml/min/1.73 m2)
81.27 ± 28.4
71 ± 22.69
Results are reported as mean ± SD, median with range or number of patients (%) as appropriate. , , , ∧ compared to patients with normoalbuminuria.
