Pravastatin Improves Glucose Regulation and Biocompatibility of Agarose Encapsulated Porcine Islets following Transplantation into Pancreatectomized Dogs

Table 1

Individual dog insulin requirements and islet macrobead information at first and second implant.

					Porcine islet macrobead Information
		Animal ID	Body weight (kg)	Daily insulin requirement (IU)	Daily insulin production (IU/bead)	Number of macrobeads implanted	Total daily insulin (IU) from implanted macrobeads	Weight of implanted macrobeads (kg)
First implant	Control	UYL-0	12.88	15	0.0378	736	27.82	0.195
		TSL-0	11.48	16	0.0378	788	29.79	0.207
		ORL-0	11.11	20	0.0378	981	37.08	0.256
	Pravastatin	VPL-0	11.61	17	0.0378	835	31.56	0.219
		UDL-0	11.39	14	0.0378	786	29.71	0.205
		UVL-0	12.79	22	0.0378	1079	40.79	0.285
Second implant	Control	UYL-0	12.93	15	0.0382	1065	40.68	0.286
		TSL-0	12.20	18	0.0382	1278	48.82	0.343
		ORL-0	11.20	18	—	—	—	—
	Pravastatin	VPL-0	12.11	22	0.0382	1565	59.78	0.415
		UDL-0	10.98	13	0.0382	923	32.26	0.245
		UVL-0	12.93	26	—	—	—	—