Research Article

BlockingαVβ3 Integrin Ligand Occupancy Inhibits the Progression of Albuminuria in Diabetic Rats

Table 1

Characteristics of study animals.

Body weight (grams ± SEM)Glucose (mg/dL ± SEM)
Start12 wks diabetes/8 wks treatmentStart1 wk diabetes12 wks diabetes/8 wks treatment

Control nondiabetic273 ± 33589 ± 15107 ± 3108 ± 5137 ± 23
Diabetic vehicle-treated 273 ± 20446 ± 18115 ± 6352 ± 36375 ± 36
Diabetic antibody-treated270 ± 21425 ± 23113 ± 7 414 ± 25425 ± 28

= 15 for each group.