Research Article
BlockingαVβ3 Integrin Ligand Occupancy Inhibits the Progression of Albuminuria in Diabetic Rats
Table 1
Characteristics of study animals.
| | Body weight (grams ± SEM) | Glucose (mg/dL ± SEM) | | Start | 12 wks diabetes/8 wks treatment | Start | 1 wk diabetes | 12 wks diabetes/8 wks treatment |
| Control nondiabetic | 273 ± 33 | 589 ± 15 | 107 ± 3 | 108 ± 5 | 137 ± 23 | Diabetic vehicle-treated | 273 ± 20 | 446 ± 18 | 115 ± 6 | 352 ± 36 | 375 ± 36 | Diabetic antibody-treated | 270 ± 21 | 425 ± 23 | 113 ± 7 | 414 ± 25 | 425 ± 28 |
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= 15 for each group.
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