Metformin Rescues the MG63 Osteoblasts against the Effect of High Glucose on Proliferation

Figure 3

ALP activity (unit/gram of protein) of MG63 cells at days 6, 12, and 18 exposed to normal glucose (NG), high glucose (HG), and metformin (300 μmol/L) treatment plus high glucose (HG + Met). Data was compared among cells at each timepoint. ^∗𝑃<0.05, HG (16.7 mmol/L) versus ctrl and NG (5.5 mmol/L). ^∗∗𝑃<0.05, HG + Met versus HG (16.7 mmol/L). ^#𝑃<0.05, HG + Met versus Ctrl and NG (5.5 mmol/L).