Ketosis Onset Type 2 Diabetes Had Better Islet 𝜷-Cell Function and More Serious Insulin Resistance

Table 1

Clinical and biochemical parameters of subjects.

Variable	Ketosis onset T2DM	Nonketotic onset T2DM	𝑃
𝑛	62	78
Age (years)	44.84±1.15	46.98±1.03	0.17
Sex (𝑛)
Male/female	41/21	56/22	0.58
BMI (kg/m^2)	25.01±0.52	24.37±0.37	0.30
SBP (mmHg)	123.24±2.14	126.78±2.39	0.30
DBP (mmHg)	82.98±1.43	82.12±1.45	0.69
HbA1c (%)	11.02±2.73	11.84±2.75	0.08
Cholesterol (mmol/L)
Total	5.37±0.14	5.65±0.17	0.13
HDL-C	1.08±0.06	1.12±0.03	0.26
LDL-C	3.29±0.14	3.44±0.12	0.88
Triglycerides (mmol/L)	2.67 (2.16)	2.07 (1.21)	0.35
ALT (U/L)	30.48±2.81	31.85±3.93	0.46
AST (U/L)	23.82±1.62	23.91±2.21	0.25
Fatty liver (𝑛)
Yes/no	36/26	31/47	0.04

Normally distributed and continuous variables (age, BMI, HbA1c, total cholesterol, LDL-cholesterol, HDL-cholesterol, ALT, and AST) were presented as mean ± SD and analyzed with ANOVA, nonnormally distributed variables (triglycerides) were expressed as median (IQR) and have been log-transformed into analysis. A Kruskal-Wallis H or Friedman test was used to analyze the nonnormally distributed variables (sex and fatty liver). In all statistical tests, 𝑃 values < 0.05 were considered statistically significant.
BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; HbA1c: hemoglobin A1c; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; ALT: alanine aminotransferase; AST: aspartate aminotransferase.