Research Article
The GLP-1 Analogue Exenatide Improves Hepatic and Muscle Insulin Sensitivity in Diabetic Rats: Tracer Studies in the Basal State and during Hyperinsulinemic-Euglycemic Clamp
Figure 3
Plasma parameters of glycerol flux and gluconeogenesis. C: nondiabetic, control; C + E: nondiabetic + exenatide; D: diabetic; D + E: diabetic + exenatide. Ra means appearance rate; GNG means gluconeogenesis. Data are presented as mean ± SD. ; compared with C group. ▲ compared with C + E group. § compared with D group. Glycerol appearance after an overnight fast was lower () in the D + E group rats than that in the D group rats (a). The gluconeogenesis from glycerol, such as glycerol converted to glucose (%) and gluconeogenesis from glycerol, was clearly lower () in the D + E group rats than that in the D group rats. (b and c). , compared with basal. , compared with C group. , compared with C + E group. §, compared with D group.
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