Evaluating the Mechanisms of Improved Glucose Homeostasis after Bariatric Surgery in Ossabaw Miniature Swine

Figure 1

Preoperative body weight and HOMA-IR in high-calorie and regular diet Ossabaws. Scatter plot of preoperative weight and HOMA-IR in pigs exposed to the high-fat, high-calorie diet for >180 days and those maintained on a normal diet. The dashed regression line shows overall mild positive correlation between weight and HOMA-IR (, ). Insulin resistance in this model was defined as HOMA-IR > 2 standard deviations above the regular diet group mean (>2.61).