Effects of Fenofibrate on Adiponectin Expression in Retinas of Streptozotocin-Induced Diabetic Rats

Figure 2

The evaluation of protein expression levels of adiponectin, adipoR1, and adipoR2 in rat retinas by western blot analysis. The protein expression levels of adiponectin and its receptors increased in the retinas of the DM group. Fenofibrate decreased the protein expression levels of adiponectin, adipoR1, and adipoR2 relative to the expression levels detected in the DM group. The -axis represents the ratios of the adiponectin, adipoR1, and adipoR2 blot densities to the β-actin blot density in each group. The sample was pooled from one eye of five rats in each group. The data are expressed as the mean ± SD of three independent experiments (bar graph). , ; DM group versus control group, fenofibrate groups versus DM group (FL: low-dose fenofibrate; FH: high-dose fenofibrate).

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