Association between eNOS 4b/a Polymorphism and the Risk of Diabetic Retinopathy in Type 2 Diabetes Mellitus: A Meta-Analysis

Table 2

The distribution of the 4b/a genotype and allele frequency for cases and controls.

Study	Distribution of 4b/a eNOS genotype						Allele frequency				HWE
	Cases			Controls			Cases		Controls
	aa	ab	bb	aa	ab	bb	a	b	a	b
Awata et al. [12]	1	25	91	3	24	82	27	207	30	188	Yes
Cheema et al. [20]	87	344	411	66	270	268	518	1166	402	806	Yes
Chen et al. [28]	10	17	41	48	136	117	37	99	232	370	Yes
Cilenšek et al. [4]	15	51	106	13	114	278	81	263	140	670	Yes
de Syllos et al. [14]	1	16	39	3	27	84	18	94	33	195	Yes
Ezzidi et al. [19]	17	115	251	33	180	276	149	617	246	732	Yes
Li et al. [26]	5	13	69	7	11	61	23	151	25	133	No
Mehrab-Mohseni et al. [21]	12	111	284	5	53	126	135	679	63	305	Yes
Petrovič et al. [18]	16	91	176	7	44	92	123	443	58	228	Yes
Santos et al. [13]	12	111	284	5	53	126	135	679	63	305	Yes
Suganthalakshmi et al. [22]	7	27	86	3	18	69	41	199	24	156	Yes
Sun et al. [24]	3	36	108	1	21	133	42	252	23	287	Yes
Uthra et al. [23]	7	54	126	1	57	130	68	306	59	317	No
Yue et al. [27]	2	27	125	4	45	118	31	277	53	281	Yes
Zhang et al. [25]	0	11	108	2	31	170	11	227	35	371	Yes

HWE: Hardy-Weinberg equilibrium, 𝑃<0.05 was considered significant.