Generating and Reversing Chronic Wounds in Diabetic Mice by Manipulating Wound Redox Parameters

Figure 5

Chronic wounds treated with individual antioxidants. (a) Wound closure in db/db chronic wounds treated with AOA α-toc was observed by day 53 after wounding. (b) Wound closure in db/db chronic wounds treated with AOA NAC was observed by day 53 after wounding. (c) Percent open wound area was calculated using Image J. Open area was significantly decreased in db/db wounds treated with IAE and then AOA. (d) Mouse weight loss was significantly higher in animals with no AOA treatment. . All data are mean ± SD. , , .

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