Impact of Bariatric Surgery on Ghrelin and Obestatin Levels in Obesity or Type 2 Diabetes Mellitus Rat Model

Figure 2

Changes of plasma ghrelin, obestatin and ghrelin/obestatin ratio after different operation treatments. (a) Ghrelin (a1), obestatin (a2) plasma levels and the ratio of ghrelin/obestatin (a3) in normal rats; (b) ghrelin (c1) and obestatin (c2) plasma levels and ghrelin/obestatin (c3) in obese rats; (c) ghrelin (d1) and obestatin (d2) plasma levels and ghrelin/obestatin (d3) in Goto-Kakisaki (GK) rats. ^##Compared with NC group preoperatively, 𝑃<0.05. ^#Compared with the same group preoperatively, 𝑃<0.05. *Compared with the same group preoperatively, 𝑃<0.01. ^&Compared with other groups preoperatively, 𝑃<0.01. SG, sleeve gastrectomy; MGBP, minigastric bypass, RYGBP, roux-en-Y gastric bypass, SO, sham operation; NC, normal control; TG, total gastrectomy.

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