JTT-130, a Novel Intestine-Specific Inhibitor of Microsomal Triglyceride Transfer Protein, Reduces Food Preference for Fat

Figure 2

Effect of JTT-130 on LF and HF diet selection during the study period. Rats were allowed to have free access to LF and HF diet. JTT-130 was administered orally to rats at a dosage of 10 mg/kg for seven days. Data are presented as means ± S.E. from ten animals. Open circle: HF diet intake in the control group; closed circle: HF diet intake in the JTT-130 group; open triangle: LF diet intake in control group; closed triangle: LF diet intake in the JTT-130 group.