JTT-130, a Novel Intestine-Specific Inhibitor of Microsomal Triglyceride Transfer Protein, Reduces Food Preference for Fat

Table 3

Effects of JTT-130 on daily macronutrient consumption during the treatment period.

	g/day		kcal/day
	Control	JTT-130	Control	JTT-130
Carbohydrate	7.0±0.4	7.7±0.4	28.1±1.5	30.8±1.7
Fat	5.9±0.2	3.9±0.2^∗∗	53.4±2.0	34.7±1.6^∗∗
Protein	4.7±0.2	4.2±0.1^∗	18.8±0.7	16.8±0.5^∗

Macronutrient analysis was performed as described in Section 2. The caloric intake from each component was calculated using calories per unit weight of 4 kcal/g of carbohydrates and protein and 9 kcal/g of fat. ^∗𝑃<0.05; ^∗∗𝑃<0.01 versus control group.