Role of MicroRNAs in Islet Beta-Cell Compensation and Failure during Diabetes

Table 1

miRNAs required for beta cell specification fate and pancreas development.

miRNAs	Known functional effect	Targets	References
mir-15a, miR-15b, miR-16, and miR-195	Pancreas development, beta-cells fate and regeneration	Neurog3	[33]
miR-375	Beta- and alpha-cells expansion		[42]
miR-7a	Beta-cell proliferation	mTOR pathway components	[44, 45, 48]
miR-124a	Pancreas development	Foxa2	[33]