Role of MicroRNAs in Islet Beta-Cell Compensation and Failure during Diabetes

Table 2

miRNAs regulating nutrient-induced insulin secretion and insulin gene expression.

miRNAs	Known functional effect	Targets	References
miR-9	Insulin secretion	Onecut-2, Sirt1	[26]
miR-21	Insulin secretion	VAMP2, Rab3a	[93]
miR-29a, b	Insulin secretion	Mctl1	[71]
miR-30d	Insulin transcription		[63]
miR-34a	Insulin secretion	VAMP2, Rab3a	[93]
miR-96	Insulin secretion	Noc2	[24]
miR-124a	Insulin secretion	Rab27a, Noc2, MCT1	[24, 71]
miR-204	Insulin transcription	MafA	[65]
miR-375	Insulin transcription, insulin secretion	PDK1, myotrophin	[22, 58]