Role of MicroRNAs in Islet Beta-Cell Compensation and Failure during Diabetes

Table 3

miRNAs associated with compensatory beta-cells.

miRNAs	Cell types/models	Expression change	Known functional effect	References
miR-132	Islets of prediabetic db/db mice	Up	Beta-cells proliferation	[84]
miR-184		Down
miR-338-3p	Islets of pregnant rats and islets of prediabetic db/db mice and obese mice fed with a high fat diet	Down	Beta-cells proliferation/antiapoptotic	[74]
	Cells cultured with estradiol or incretins
miR-451	Islets of pregnant rats, islets of prediabetic db/db mice and obese mice fed with a high fat diet	Up	Antiapoptotic	[74]