Effect of Ranirestat, a New Aldose Reductase Inhibitor, on Diabetic Retinopathy in SDT Rats

Figure 1

Body weight of the study animals. The SD rats are heavier than the SDT rats with or without treatment. NDM: normal SD rats; DM: untreated SDT rats; rani (0.1): ranirestat-treated SDT rats (0.1 mg/kg/day); rani (1.0): ranirestat-treated SDT rats (1.0 mg/kg/day); rani (10): ranirestat-treated SDT rats (10 mg/kg/day); epa (100): epalrestat-treated SDT rats (100 mg/kg/day) [21].