Research Article

Pharmacological Effects of JTT-551, a Novel Protein Tyrosine Phosphatase 1B Inhibitor, in Diet-Induced Obesity Mice

Figure 2

Enhancement effects of JTT-551 on STAT3 phosphorylation in the hypothalamus of DIO mice. The detected bands (typical bands) are shown in (a) and the phosphorylation-STAT3/STAT3 in each group in (b). The intensity of the STAT3 phosphorylation was calculated as the ratio of the density of phosphorylation-STAT3 to the density of STAT3.
680348.fig.002a
(a)
680348.fig.002b
(b)