Characterization of Diabetic Neuropathy in the Zucker Diabetic Sprague-Dawley Rat: A New Animal Model for Type 2 Diabetes

Figure 4

Corneal nerve fiber length and corneal sensitivity in age-matched Sprague Dawley and ZDSD rats. Corneal nerve fiber length (a) and corneal sensitivity (b) were examined as described in the Methods section in Sprague Dawley (SD) and ZDSD rats. Inserts are representative images of the subepithelial layer of the cornea from Sprague-Dawley (left) and ZDSD (right) rats. The red arrows point out the corneal nerves. The number of rats in each group was 10 and 9, respectively. Data are presented as the mean ± S.E.M. for corneal nerve fiber length in mm/mm² and corneal sensitivity in cm. compared to Sprague Dawley rats.