Research Article

Characterization of Diabetic Neuropathy in the Zucker Diabetic Sprague-Dawley Rat: A New Animal Model for Type 2 Diabetes

Table 1

Vital parameters for Sprague Dawley and ZDSD rats.

DeterminationSprague Dawley
(10)
ZDSD
(9)

Start weight (g)
End weight (g)
Blood glucose (mg/dL)
Hb A1C (%)
Serum free fatty acid (mmol/L)
Serum triglycerides (mg/dL)
Serum free cholesterol (mg/mL)
Liver oil red staining
(% of total area)
Sciatic nerve nitrotyrosine
(arbitrary light units)

For these studies there were 2 groups: Sprague Dawley (control) and ZDSD rats. Data are presented as the mean ± S.E.M. compared to control. The number of animals in each group is shown in parenthesis.