Altered Expression Profile of Renal -Adrenergic Receptor in Diabetes and Its Modulation by PPAR Agonists
Figure 5
Increased tubulointerstitial -AR staining in the kidney of 20-week-old Zucker diabetic rats. In the diabetic kidneys, an induction of -AR protein (green) was detected in the epithelium of dilated tubules as well as the surrounding interstitial cells, which are -SMA-positive (dark blue). Images in (a′), (b′), and (c′) are enlarged from the boxed areas in (a), (b), and (c).
