Evaluation of Hypoglycemic Efficacy of Tangningtongluo Formula, a Traditional Chinese Miao Medicine, in Two Rodent Animal Models

Figure 12

Pathological examination of renal tubule in db/db mice. (a) Renal tubule from a normal mouse. (b) Edema and degeneration of renal tubular epithelial cell from db/db mouse with no treatment. (c) Edema and degeneration of renal tubular epithelial cell from metformin-treated db/db mouse. (d), (e), and (f) Alleviation of degeneration of renal tubular epithelial cell from TNTL-treated db/db mouse at the dose of 3.6 g, 1.8 and 0.9 g/kg b.w., respectively.

(a)

(b)

(c)

(d)

(e)

(f)