Evaluation of Hypoglycemic Efficacy of Tangningtongluo Formula, a Traditional Chinese Miao Medicine, in Two Rodent Animal Models

Figure 6

Lipid profile in db/db mice. The TNTL (TNTL-h, m, l means the dose of 3.6 g, 1.8 and 0.9 g/kg b.w., resp.) administration leads to reductions in plasma levels of triglycerides (a), total cholesterol (b), and low-density lipoprotein (c), respectively, compared to the model group. Mice treated with TNTL (3.6 g/kg) showed significant reductions in total cholesterol (TC), CHO, and low-density lipoproteins (LDL) (25%, 11%, and 10%, resp.), compared to controls. Control: C57BL, DM: db/db mice with untreated, Met: db/db mice treated with metformin, and TNTL-h, m, l: db/db mice treated with 3.6 g, 1.8 and 0.9 g/kg b.w., respectively. compared with DM group. compared with control group.

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