Hyperglycemia Inhibits Complement-Mediated Immunological Control of S. aureus in a Rat Model of Peritonitis

Figure 1

(a) Rat treatment groups and timeline for streptozocin induction, infection, insulin rescue (NPH), and peritoneal lavage. (b) Blood glucose levels for the four groups of rats: euglycemic, diabetic (2 hr), insulin rescue, and diabetic (24 hr). Streptozocin (STZ) was given to all rats except the euglycemic group at −24 hours. Zero hour is time of infection. Insulin (NPH) was given to the insulin rescue group at 2 hours and 8 hours after infection.

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