Insulin Increases Ceramide Synthesis in Skeletal Muscle
Figure 6
Adult male mice (12 weeks) were divided into two groups to receive insulin (INS, 50 nM) or vehicle (PBS) injections every morning for 14 d. Soleus levels of genes of multiple enzymes involved with ceramide (SPT1, SPT2, and DES1) and TAG (DGAT1 and FAS) metabolism were quantified. , INS versus PBS.
