Brain Aging and AD-Like Pathology in Streptozotocin-Induced Diabetic Rats
Figure 4
Aβ42 deposition in rat hippocampus at 4 months after STZ injection. (a) Representative images of Aβ42 immunoreaction in the frontal cortex: black square was magnified and shown in red square; blue arrow indicates the glial cells. (b) Representative images of Aβ42 immunoreaction in the hippocampus: black square was magnified and shown in red square, blue arrow indicates the glial cells, and black arrow indicates the neuron. (c) Aβ42 was quantified in soluble and insoluble fractions of the cortex by ELISA. (d) Aβ42 was quantified in soluble and insoluble fractions of the hippocampus by ELISA. , significant difference compared with the age-matched control rats; .
