Brain Aging and AD-Like Pathology in Streptozotocin-Induced Diabetic Rats
Evaluation of the cognition of diabetic rats at 4 months after STZ injection. (a) Representative traces by the Morris water maze. The performance of rats in the Morris water maze using hidden platform training for 4 d was assessed based on (b) escape latency and (c) swimming velocity in the normal and DM groups. (d) Freezing duration was measured using inhibitory avoidance box. , significant difference compared with the age-matched control rats; , significant difference compared with the age-matched control rats; .