MG132 Ameliorates Kidney Lesions by Inhibiting the Degradation of Smad7 in Streptozotocin-Induced Diabetic Nephropathy

Figure 2

Transmission electron microscopy of the kidney tissue (×10,000). Hydropic endothelial cells and podocytes, endothelial pore broadening, irregular thickening and decrease in the electronic density of the basement membrane, and partial foot process fusion were visualized in the experimental groups (red arrow), especially in the diabetic nephropathy group, but were found to be recovered in the MH group.