Review Article
The Role of MicroRNAs in Diabetic Nephropathy
Table 1
Upregulated miRNAs.
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STZ: streptozotocin; δEF1: deltaEF1 (ZEB1); FOG: Friend of GATA; SIP1: Smad-interacting protein 1; Col: collagen; ZEB1/2: zinc finger E-box binding homeobox 1/2; YBX1: Y box binding protein 1; α-SMA: alpha smooth muscle actin; PTEN: phosphatase and tensin homolog; p-Akt: phosphorylated protein kinase B; PRAS40: proline-rich Akt substrate 40; mTORC1: mechanistic target of rapamycin complex 1; SMAD3: mothers against decapentaplegic homolog 3; SMAD7: mothers against decapentaplegic homolog 7; TIMP: tissue inhibitors of metalloproteinase; PAK1: p21 activated kinase; SOD: superoxide dismutase; BCL2: B-cell CLL/lymphoma 2; INTEGRIN31: integrin alpha 3 beta 1; SPRY1: Sprouty homolog 1; NF-κB: nuclear factor kappa B; TGF-β: transforming growth factor beta; ERK: extracellular signal-regulated kinases; ECM: extracellular matrix; FN: fibronectin; PAI-1: plasminogen activator inhibitor-1; MMC: mouse mesangial cell; HMC: human mesangial cell; RMC: rat mesangial cell; ACR: albumin creatinine ratio; CCR: creatinine clearance ratio; TRPC1: transient receptor potential cation channel, subfamily C, member 1. |