Research Article
Urinary Methylmalonic Acid as an Indicator of Early Vitamin B12 Deficiency and Its Role in Polyneuropathy in Type 2 Diabetes
Table 4
The correlation analysis between urinary methylmalonic acid/creatinine and electrophysiological markers of neuropathy severity.
| Electrophysiological markers of neuropathy severity | r | P |
| Sural nerve SNAP amplitude (μV) | −0.131 | −0.06 | Sural nerve sensory conduction velocity (m/s) | −0.120 | −0.065 | Sural nerve CMAP amplitude (μV) | −0.196 | −0.02 | Sural nerve motor conduction velocity (m/s) | −0.205 | −0.01 | Superficial peroneal nerve SNAP amplitude (μV) | −0.0034 | −0.69 | Superficial peroneal nerve sensory conduction velocity (m/s) | −0.496 | −0.0005 | Superficial peroneal nerve CMAP amplitude (μV) | −0.197 | −0.015 | Superficial peroneal nerve motor conduction velocity (m/s) | −0.327 | −0.003 | Median nerve sensory conduction velocity (m/s) | −0.115 | −0.07 | Median nerve SNAP amplitude (μV) | −0.089 | −0.15 | Median nerve motor conduction velocity (m/s) | −0.139 | −0.055 | Median nerve CMAP amplitude (μV) | −0.002 | −0.86 | Ulnar nerve sensory conduction velocity (m/s) | −0.187 | −0.02 | Ulnar nerve CMAP amplitude (μV) | −0.315 | −0.005 | Ulnar nerve motor conduction velocity (m/s) | −0.009 | −0.60 | Ulnar nerve SNAP amplitude (μV) | −0.125 | −0.065 |
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SNAP: sensory active nerve potential; CMAP: compound motor active potential.
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