Research Article

Urinary Methylmalonic Acid as an Indicator of Early Vitamin B12 Deficiency and Its Role in Polyneuropathy in Type 2 Diabetes

Table 4

The correlation analysis between urinary methylmalonic acid/creatinine and electrophysiological markers of neuropathy severity.

Electrophysiological markers of neuropathy severityr P

Sural nerve SNAP amplitude (μV)−0.131−0.06
Sural nerve sensory conduction velocity (m/s)−0.120−0.065
Sural nerve CMAP amplitude (μV)−0.196−0.02
Sural nerve motor conduction velocity (m/s)−0.205−0.01
Superficial peroneal nerve SNAP amplitude (μV)−0.0034−0.69
Superficial peroneal nerve sensory conduction velocity (m/s)−0.496−0.0005
Superficial peroneal nerve CMAP amplitude (μV)−0.197−0.015
Superficial peroneal nerve motor conduction velocity (m/s)−0.327−0.003
Median nerve sensory conduction velocity (m/s)−0.115−0.07
Median nerve SNAP amplitude (μV)−0.089−0.15
Median nerve motor conduction velocity (m/s)−0.139−0.055
Median nerve CMAP amplitude (μV)−0.002−0.86
Ulnar nerve sensory conduction velocity (m/s)−0.187−0.02
Ulnar nerve CMAP amplitude (μV)−0.315−0.005
Ulnar nerve motor conduction velocity (m/s)−0.009−0.60
Ulnar nerve SNAP amplitude (μV)−0.125−0.065

SNAP: sensory active nerve potential; CMAP: compound motor active potential.