Sodium Meta-Arsenite Ameliorates Hyperglycemia in Obese Diabetic db/db Mice by Inhibition of Hepatic Gluconeogenesis

Figure 6

Maintenance of a low level of energy expenditure in SA-treated db/db mice. Diabetic db/db mice were treated with SA. (a) Food intake, (b) oxygen consumption (VO₂), (c) carbon dioxide output (VCO₂), (d) energy expenditure (EE), and (e) respiratory exchange ratio (RER) were measured by indirect calorimetry analysis for 72 h at 8 weeks of SA treatment (-8/group). , , and compared with untreated mice; , compared with the pair-fed group.

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